Mechanistic fracture criteria for the failure of human cortical bone

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Mechanistic fracture criteria for the failure of human cortical bone.

A mechanistic understanding of fracture in human bone is critical to predicting fracture risk associated with age and disease. Despite extensive work, a mechanistic framework for describing how the microstructure affects the failure of bone is lacking. Although micromechanical models incorporating local failure criteria have been developed for metallic and ceramic materials, few such models exi...

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A fracture mechanics and mechanistic approach to the failure of cortical bone

A B S T R A C T The fracture of bone is a health concern of increasing significance as the population ages. It is therefore of importance to understand the mechanics and mechanisms of how bone fails, both from a perspective of outright (catastrophic) fracture and from delayed/time-dependent (subcritical) cracking. To address this need, there have been many in vitro studies to date that have att...

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Fracture in human cortical bone: local fracture criteria and toughening mechanisms.

Micromechanical models for fracture initiation that incorporate local failure criteria have been widely developed for metallic and ceramic materials; however, few such micromechanical models have been developed for the fracture of bone. In fact, although the fracture event in "hard" mineralized tissues such as bone is commonly believed to be locally strain-controlled, only recently has there be...

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Mixed-mode fracture of human cortical bone.

Although the mode I (tensile opening) fracture toughness has been the focus of most fracture mechanics studies of human cortical bone, bones in vivo are invariably loaded multiaxially. Consequently, an understanding of mixed-mode fracture is necessary to determine whether a mode I fracture toughness test provides the appropriate information to accurately quantify fracture risk. In this study, w...

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Mechanistic aspects of fracture and R-curve behavior in human cortical bone.

An understanding of the evolution of toughness is essential for the mechanistic interpretation of the fracture of cortical bone. In the present study, in vitro fracture experiments were conducted on human cortical bone in order to identify and quantitatively assess the salient toughening mechanisms. The fracture toughness was found to rise linearly with crack extension (i.e., rising resistance-...

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ژورنال

عنوان ژورنال: Nature Materials

سال: 2003

ISSN: 1476-1122,1476-4660

DOI: 10.1038/nmat832